Procurou por: Nonidet®+P+40+Substitute+(NP-40)

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Anti-HSP 40-4/HDJ2/DNAJA1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Código de Artigo: (BOSSBS-11277R-A680)

Fornecedor: Bioss

Descrição: DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen Signalling.

UOM: 1 * 100 µl

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VWR®, Objectives for Microscope BI 100

Fornecedor: VWR Collection

Descrição: Achromatic objective, VWR®, 40×

Hidróxido de sódio 40% em solução aquosa, BAKER, Reagente de Laboratório, J.T.Baker®

Código de Artigo: (6165.9010)

Fornecedor: Avantor

Descrição: Hidróxido de sódio 40% em solução aquosa, BAKER, Reagente de Laboratório, J.T.Baker®

UOM: 1 * 10 L

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Anti-NPS Rabbit Polyclonal Antibody (Cy3®)

Código de Artigo: (BOSSBS-11429R-CY3)

Fornecedor: Bioss

Descrição: Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.

UOM: 1 * 100 µl

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