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Image Unavailable-BOSSBS-1302R-HRP

Anti-GAD1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Código de Artigo: (BOSSBS-1302R-HRP)
Fornecedor: Bioss
Descrição: Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
UOM: 1 * 100 µl
Imagem do Produto-PRSI30-484

Anti-ALG2 Rabbit Polyclonal Antibody

Código de Artigo: (PRSI30-484)
Fornecedor: ProSci Inc.
Descrição: ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1,3 mannosyltransferase, mannosylating Man (2)GlcNAc (2)-dolichol diphosphate and Man (1)GlcNAc (2)-dolichol diphosphate to form Man (3)GlcNAc (2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man (2)GlcNAc (2)-dolichol diphosphate and Man (1)GlcNAc (2)-dolichol diphosphate to form Man (3)GlcNAc (2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM: 1 * 50 µG
Imagem do Produto-612-0683

Sistemas de aspiração a vácuo VACUBOY

Fornecedor: Integra
Descrição: O operador manual VACUBOY é ideal para a aspiração e a sucção absolutas, e com todo o controlo e segurança, de qualquer líquido de cuvetes, placas para microtitulação, tubos de ensaio, caixas de Petri, garrafas de cultura de células, garrafas rotativas, biorreactores e outros recipientes típicos para laboratório. Foi concebido para a utilização com variadíssimos adaptadores de aspiração de aço inoxidável, pipetas serológicas e Pasteur e pontas de pipeta para uma vastíssima gama de aplicações. Cada adaptador foi especialmente concebido em função das dimensões e da geometria dos respectivos recipientes para laboratório de vidro ou de plástico. O operador manual pode ser conectado a qualquer fonte de vácuo ainda no laboratório, servindo, assim, para melhorar as instalações existentes.

Imagem do Produto-512-3301

Vacuum filter holders, stainless steel

Fornecedor: Sartorius
Descrição: Para contagem de colónias e colheita de partículas, especialmente concebido para aplicações em que são relevantes as partículas ou os microrganismos retidos na superfície da membrana filtrante. O suporte de aço inoxidável da membrana garante distribuição uniforme do filtrado.

Imagem do Produto-132-0405

VWR® All-In-One line, Cadeiras, bancos

Fornecedor: VWR Collection
Descrição: Todas as cadeiras e bancos estão disponíveis com uma base em estrela, feita de tubos de aço seccionais e de resistência elevada, sendo particularmente robusta e duradoura. O design plano evita os perigos de tropeçamento.

Imagem do Produto-554-2152

Injetores de amostras, Rheodyne®

Fornecedor: IDEX RHEODYNE
Descrição: Os injetores de amostras manuais têm duas posições, 'Load' e 'Inject'. A posição 'Load' permite o carregamento da amostra no loop. É comum usar-se uma seringa para carregar a amostra no injetor de amostras. Após o carregamento, a rotação manual do punho do injetor de amostras para a posição 'Inject' permite lançar a amostra carregada para dentro da coluna.

Image Unavailable-BOSSBS-1302R-A647

Anti-GAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Código de Artigo: (BOSSBS-1302R-A647)
Fornecedor: Bioss
Descrição: Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1302R-FITC

Anti-GAD1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Código de Artigo: (BOSSBS-1302R-FITC)
Fornecedor: Bioss
Descrição: Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
UOM: 1 * 100 µl
Imagem do Produto-113-8143

Máscaras faciais para salas brancas, Kimtech™ M3

Fornecedor: KIMBERLY CLARK
Descrição: Máscaras plissadas que proporcionam uma filtração comprovada de partículas para evitar a contaminação.

Imagem do Produto-PRSI26-488

Anti-RFT1 Rabbit Polyclonal Antibody

Código de Artigo: (PRSI26-488)
Fornecedor: ProSci Inc.
Descrição: N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a¡¡Man (5)GlcNAc (2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man (5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation.N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of a Man (5)GlcNAc (2)-dolichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic reticulum (ER) membrane followed by the translocation of Man (5)GlcNAc (2)-PP-Dol to the luminal side of the ER membrane. RFT1 is the flippase enzyme that catalyzes this translocation (Helenius et al., 2002 [PubMed 11807558]).
UOM: 1 * 50 µG
Imagem do Produto-PROMA1331

Accessories for laboratory vacuum manifold, Vac-Man®

Código de Artigo: (PROMA1331)
Fornecedor: Promega
Descrição: Vacuum adapters
UOM: 1 * 20 unid.
Imagem do Produto-132-0418

VWR®, Lab-Office, Cadeiras com estofamento em tecido de alta qualidade

Código de Artigo: (132-0418)
Fornecedor: VWR Collection
Descrição: Estas cadeiras estão disponíveis com uma base em estrela feita de tubos seccionais de alta resistência, particularmente robustos e duráveis. O design plano evita riscos de tropeços.
UOM: 1 * 1 unid.
Image Unavailable-JALCJIJI512/46

ESD Safety Shoes, Slip-on, JALQUARTZ

Fornecedor: Jallatte
Descrição: Loafer safety shoe incorporating MAXI-Soft Duo anti-fatigue technology designed for work stations that require standing for long periods (Upright or sustained activity).

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Image Unavailable-BOSSBS-1302R-A488

Anti-GAD1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Código de Artigo: (BOSSBS-1302R-A488)
Fornecedor: Bioss
Descrição: Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
UOM: 1 * 100 µl
Imagem do Produto-PRSI26-154

Anti-MOGS Rabbit Polyclonal Antibody

Código de Artigo: (PRSI26-154)
Fornecedor: ProSci Inc.
Descrição: GCS1 is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3)-Man (9)-GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3)-Man (9)-GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum.
UOM: 1 * 50 µG
Imagem do Produto-PRSI28-457

Anti-FERD3L Rabbit Polyclonal Antibody

Código de Artigo: (PRSI28-457)
Fornecedor: ProSci Inc.
Descrição: FERD3L is an evolutionarily conserved bHLH transcription factor that is identified in fly, mouse and man. Nervous system expression of this protein is detected in fly and mouse.
UOM: 1 * 50 µG
Preço sob consulta
O stock para este item é limitado. Por favor, certifique-se de que efetuou o seu login para visualizar o stock disponível. Se a call ainda é exibida e precisar de ajuda, por favor, ligue para 213 600 770
O stock para este item é limitado. Por favor, certifique-se de que efetuou o seu login para visualizar o stock disponível. Se a call está visível e precisar de ajuda, por favor, ligue para 213 600 770
Este produto é sujeito a regulamentação especifica.
Em caso de encomenda, será contactado a solicitar documentação complementar necessária e/ou obrigatória (licença, autorização ou declaração de uso final) para a continuidade do pedido. Agradecemos a vossa compreensão
Este produto é sujeito a regulamentação especifica.
Em caso de encomenda, será contactado a solicitar documentação complementar necessária e/ou obrigatória (licença, autorização ou declaração de uso final) para a continuidade do pedido. Agradecemos a vossa compreensão.
Este produto está bloqueado. Para obter mais informações, contacte a VWR através do número 213 600 770.
O produto pretendido já não se encontra disponível. O produto indicado é um substituto.
Este produto encontra-se em rutura de stock. Poderá encontrar alternativas pesquisando pelo código de artigo indicado acima. Se precisar de ajuda, por favor contacte a VWR através do 213 600 770.
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