Procurou por: Separadores+Centr\\u00EDfugos

Código de Artigo: (HECH51071012)

Fornecedor: GLASWARENFABRIK KARL HECHT

Descrição: These gauzes are made of galvanised iron wire and feature a ceramic centre.

UOM: 1 * 1 unid.

Promoção

Código de Artigo: (BOSSBS-0087R-CY7)

Fornecedor: Bioss

Descrição: The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF). Alternative splicing of this gene results in two transcript variants which encode the same protein. In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e.g. commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts). Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells). Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

UOM: 1 * 100 µl

Promoção

Fornecedor: VWR Collection

Descrição: Tabuleiros e separadores para tubos estreitos

Fornecedor: Welch by Gardner Denver

Descrição: Centring rings made of stainless steel, with filter fleece and perbunan O-ring.

Fornecedor: VWR Collection

Descrição: O shiroGEL vertical 20 é conveniente para multiplas aplicações e distingue-se pela facilidade de moldagem e montagem do gel, necessitando apenas de quatro parafusos para fixar até quatro géis de 20×20 cm. Esta tecnologia de parafuso na vertical distribui a pressão uniformemente ao longo da altura do gel e não no centro, para eliminar qualquer deformação da placa e compressão do gel, mantendo a vedação durante o "casting". Uma câmara interna de tampão incorporada no inserto PAGE permite completar a montagem sem a inclusão de uma câmara de tampão na parte superior. Estes sistemas são ideais para electroforese de ácidos nucleicos de alta resolução, de gradiente, nativa, preparativa 1D e 2D SDS-PAGE.

Código de Artigo: (BOSSBS-0087R-A350)

Fornecedor: Bioss

Descrição: The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF). Alternative splicing of this gene results in two transcript variants which encode the same protein. In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e.g. commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts). Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells). Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-0087R-A488)

Fornecedor: Bioss

Descrição: The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF). Alternative splicing of this gene results in two transcript variants which encode the same protein. In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e.g. commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts). Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells). Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-0087R-A647)

Fornecedor: Bioss

Descrição: The caspase family of cysteine proteases play a key role in apoptosis. Caspase 3 is the most extensively studied apoptotic protein among caspase family members. Caspase 3 is synthesized as inactive pro enzyme that is processed in cells undergoing apoptosis by self proteolysis and/or cleavage by other upstream proteases (e.g. Caspases 8, 9 and 10). The processed form of Caspase 3 consists of large (17kDa) and small (12kDa) subunits which associate to form an active enzyme. Caspase 3 is cleaved at Asp28 Ser29 and Asp175 Ser176. The active Caspase 3 proteolytically cleaves and activates other caspases (e.g. Caspases 6, 7 and 9), as well as relevant targets in the cells (e.g. PARP and DFF). Alternative splicing of this gene results in two transcript variants which encode the same protein. In immunohistochemical studies Caspase 3 expression has been shown to be widespread but not present in all cell types (e.g. commonly reported in epithelial cells of skin, renal proximal tubules and collecting ducts). Differences in the level of Caspase 3 have been reported in cells of short lived nature (eg germinal centre B cells) and those that are long lived (eg mantle zone B cells). Caspase 3 is the predominant caspase involved in the cleavage of amyloid beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

UOM: 1 * 100 µl

Promoção

Fornecedor: DWK Life Sciences

Descrição: Aluminum seals (unlined) are available in a wide range of styles and sizes.

Fornecedor: VACUUBRAND

Descrição: These adapting centring rings for small flange connections with sealing ring made of FKM.

Fornecedor: Lenz Laborglas GmbH & CO.KG

Descrição: DURAN®, vidro borosilicato, com gargalo lateral angulado, transparente.

Código de Artigo: (USBE5072)

Fornecedor: USBECK Laborgeräte

Descrição: Mesh from galvanised steel wire.

UOM: 1 * 1 unid.

Novo produto Promoção

Fornecedor: DRUMMOND

Descrição: Stainless steel/PTFE manifolds allow multiple test positions to be fed, rinsed, or aspirated quickly and easily.

Código de Artigo: (BOSSBS-3948R-A680)

Fornecedor: Bioss

Descrição: Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal centre in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarisation by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (PPSA3500095)

Fornecedor: PFENNIG REINIGUNGSTECHNIK

Descrição: Carrinhos, Holder frame for Clino PlusBox, electropolished stainless steel, fix PlusBox at center

UOM: 1 * 1 unid.

Promoção

Fornecedor: GLASWARENFABRIK KARL HECHT

Descrição: PTFE coated, magnetic stirring bars.