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Dynasore ≥98% (por RMN)

Fornecedor: ENZO LIFE SCIENCES

Sinônimos: N'-(3,4-Dihydroxybenzylidene)-3-hydroxy-2-naphthohydrazide, 3-Hydroxynaphthalene-2-carboxylic acid (3,4-Dihydroxybenzylidene)hydrazide

ALX270502M005 ALX270502M025
ENZOALX270502M005EA 73.7 EUR
ENZOALX270502M005 ENZOALX270502M025
Dynasore ≥98% (por RMN)
Dynasore

GTPase inhibitor


Small molecule GTPase inhibitor targeting Dynamin-1, Dynamin-2 and Drp1 (mitochondrial Dynamin). Noncompetitive inhibitor of Dynamin GTPase activity. Blocks Dynamin-dependent endocytosis in cells (including neurons). Fast acting (seconds). Strong, dose dependent block of the traffic and accumulation of transferrin with 80µM dynasore (IC50 = 15µM). Has also been shown to block human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.

Fórmula: C₁₈H₁₄N₂O₄
Número MDL : MFCD00292551
Número CAS: 304448-55-3

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