Procurou por: STEMCELL TECHNOLOGIES

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Interleukin 1 beta (IL-1β) is synthesized as an inactive precursor protein or pro-IL-1β. This precursor is cleaved intracellularly by caspase 1 (IL-1β convertase) to form the active form of the protein that is later secreted (Allan <i>et al.</i>). IL-1β binds to IL-1 receptor and activates intracellular signaling via the MAPK or NF-κB pathway. IL-1β is released by monocytes, tissue macrophages, and dendritic cells in response to infection or injury and induces expression of acute-phase proteins. It also promotes the infiltration of inflammatory and immunocompetent cells from the circulation into the extravascular space and affected tissues, by stimulating the expression of adhesion molecules on endothelial cells. IL-1β also affects other immune cells; for example, it co-stimulates T cell functions together with an antigen or mitogen. It also stimulates Th17 differentiation and B cell proliferation in an IL-6-dependent manner.

Novo produto

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Interleukin 2 (IL-2) is a monomeric cytokine that was originally identified as a T cell growth factor (Gaffen and Liu). It binds to heterotrimeric receptors consisting of CD25, CD122, and CD132. Upon binding, it activates JAK3-, STAT5-, and AKT-dependent signaling pathways, which results in cellular proliferation and survival (Ma <i>et al.</i>). The majority of IL-2 is secreted by activated CD4+ and CD8+ T cells, although B cells and dendritic cells were found to produce IL-2 in small amounts. IL-2 downregulates immune responses to prevent autoimmunity during thymic development, influences the development of CD4+CD25+ regulatory T cells, and affects development of follicular helper T cells. IL-2 also controls inflammation by inhibiting Th17 differentiation (Banchereau <i>et al.</i>). High IL-2 levels in serum are associated with progression of scleroderma, rheumatoid arthritis, and gastric and non-small cell lung cancer, though no known disease can be directly attributed to the lack or excess of IL-2 (Gaffen and Liu).

Código de Artigo: (STMC03990)

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Animal component-free suspension culture medium for human ES and iPS cells.

UOM: 1 * 1 KIT

Promoção

 This is a MarketSource item. Additional charges may apply

Código de Artigo: (STMC100-0031)

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Immunomagnetic positive selection of particle-free human cells labeled with APC-conjugated antibodies.

UOM: 1 * 1 KIT

Promoção

 This is a MarketSource item. Additional charges may apply

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Immunomagnetic positive selection of particle-free CD45+ leukocytes from primary human tissues and tumors.

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Immunomagnetic positive selection of any cells labeled with biotinylated antibodies.

Código de Artigo: (STMC17865)

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Immunomagnetic positive selection of human central and effector memory CD4+ T cells.

UOM: 1 * 1 KIT

Promoção

 This is a MarketSource item. Additional charges may apply

Código de Artigo: (STMC17869)

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Immunomagnetic positive selection of human central and effector memory CD8+ T cells.

UOM: 1 * 1 KIT

Promoção

 This is a MarketSource item. Additional charges may apply

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Column-free immunomagnetic positive selection of human CD4+ cells for HLA analysis.

Código de Artigo: (STMC01350)

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Mouse monoclonal antibody to human erythropoietin.

UOM: 1 * 0,1 mL

Promoção

 This is a MarketSource item. Additional charges may apply

Código de Artigo: (STMC04534)

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Methylcellulose-based medium with recombinant cytokines (without EPO) for human cells. 1×100 ml bottle.

UOM: 1 * 100 mL

Promoção

 This is a MarketSource item. Additional charges may apply

Código de Artigo: (STMC20144)

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: EasySep™ buffer is recommended for EasySep™ cell separation protocols.

UOM: 1 * 1 L

Promoção

 This is a MarketSource item. Additional charges may apply

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Immunodensity isolation of untouched B cells.

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: For depletion of red blood cells from fresh blood samples and isolation of nucleated cells.

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: Immunomagnetic isolation of untouched mouse stem/progenitor cells

Código de Artigo: (STMC100-0670)

Fornecedor: STEMCELL TECHNOLOGIES

Descrição: The EBV (BZLF1) peptide pool is a lyophilised mixture of 59 peptides from trans-activator protein BZLF1 of Epstein-Barr virus (EBV; strain B95-8). BZLF1 is a DNA-binding protein that acts as a switch from latent infection to lytic infection. The pool consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 245 on BZLF1.

UOM: 1 * 1 KIT

Promoção

 This is a MarketSource item. Additional charges may apply