Procurou por: spectramax+reader

Fornecedor: MOLECULAR DEVICES

Descrição: EarlyTox™ Cell Viability Assay Kits are a family of fluorescence-based reagents for the assessment of cell viability, cell proliferation, and various apoptosis events using mammalian cells. Optimised for use with microplate readers, these assay kits employ a no-wash, homogeneous assay protocol that enables characterisation of a full concentration-response profile of test compounds.

Código de Artigo: (BOSSBS-15013R-A680)

Fornecedor: Bioss

Descrição: Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-7697R-A680)

Fornecedor: Bioss

Descrição: Chromatin reader that specifically recognises and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalises with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (AATB22971)

Fornecedor: AAT BIOQUEST

Descrição: Mitochondria are major producers of cellular superoxide.

UOM: 1 * 200 Tests

Promoção

Código de Artigo: (BOSSBS-15013R-CY5)

Fornecedor: Bioss

Descrição: Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.

UOM: 1 * 100 µl

Promoção

Fornecedor: THERMO LABSYSTEMS LIFE SCIENCE

Descrição: Optical filters, 340 nm

Código de Artigo: (BOSSBS-15013R-A350)

Fornecedor: Bioss

Descrição: Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (MLDVR8346)

Fornecedor: MOLECULAR DEVICES

Descrição: EarlyTox™ Cell Viability Assay Kits are a family of fluorescence-based reagents for the assessment of cell viability, cell proliferation, and various apoptosis events using mammalian cells. Optimised for use with microplate readers, these assay kits employ a no-wash, homogeneous assay protocol that enables characterisation of a full concentration-response profile of test compounds.

UOM: 1 * 1 KIT

Promoção

Código de Artigo: (BOSSBS-15013R-A647)

Fornecedor: Bioss

Descrição: Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (AATB17650)

Fornecedor: AAT BIOQUEST

Descrição: Helixyte™ Green dsDNA Quantitation Assay Kit can be used for selectively detecting as little as 25 pg/ml of dsDNA in the presence of ssDNA, RNA, and free nucleotides.

UOM: 1 * 200 Tests

Promoção

Código de Artigo: (AATB36312)

Fornecedor: AAT BIOQUEST

Descrição: Cell Meter™ No Wash and Probenecid-Free Endpoint Calcium Assay Kit enables homogeneous fluorescence-based assays for detecting intracellular calcium mobilization without the need to use kinetics reading mode.

UOM: 1 * 100 Tests

Promoção

Código de Artigo: (AATB16350)

Fornecedor: AAT BIOQUEST

Descrição: Nitric oxide (NO) is an important biological regulator involved in numbers of physiological and pathological processes.

UOM: 1 * 200 Tests

Promoção

Código de Artigo: (620-1965)

Fornecedor: VWR Collection

Descrição: Este registador de dados autónomo regista as leituras num cartão SD amovível. Um leitor de cartões (fornecido) liga a qualquer porta USB do computador para gerar um relatório imediato.

UOM: 1 * 1 unid.

Promoção

Código de Artigo: (AATB14016)

Fornecedor: AAT BIOQUEST

Descrição: MUGlcU is a fluorogenic MU substrate for detecting glucuronidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer.

UOM: 1 * 5 mg

Promoção

Fornecedor: Thermo Scientific

Descrição: Centri-Log™ data collection software is a paperless process tracking and compliance solution. This innovative software provides effective quality control for the documentation (logging and monitoring) of centrifugation processes, enabling lifecycle management of processed samples, equipment optimisation, and compliance with standard operating procedures.

Fornecedor: Thermo Fisher Scientific

Descrição: OPD (o-phenylenediamine dihydrochloride) is a water-soluble substrate for horseradish peroxidase (HRP) that produces a yellow-orange product detectable at 492 nm by ELISA plate readers.