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Imagem do Produto-PRSI26-047

Anti-TFR2 Rabbit Polyclonal Antibody

Descrição: TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Código de Artigo: PRSI26-047
UOM: 1 * 50 µG
Fornecedor: ProSci Inc.
Image Unavailable-BOSSBS-0638R-A555

Anti-TGFRB1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Descrição: Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
Código de Artigo: BOSSBS-0638R-A555
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-0638R-FITC

Anti-TGFRB1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Descrição: Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
Código de Artigo: BOSSBS-0638R-FITC
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-0638R-A647

Anti-TGFRB1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Descrição: Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
Código de Artigo: BOSSBS-0638R-A647
UOM: 1 * 100 µl
Fornecedor: Bioss
Imagem do Produto-PRSI26-048

Anti-TFR2 Rabbit Polyclonal Antibody

Descrição: TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Código de Artigo: PRSI26-048
UOM: 1 * 50 µG
Fornecedor: ProSci Inc.
Image Unavailable-SIAL379875-1G

Palladium(II) acetate, Sigma-Aldrich®

Descrição: Palladium(II) acetate, Sigma-Aldrich®
Código de Artigo: SIAL379875-1G
UOM: 1 * 1 g
Fornecedor: Merck
Image Unavailable-SIAL517933-25G

Iron(II) acetate, Sigma-Aldrich®

Descrição: Iron(II) acetate, Sigma-Aldrich®
Código de Artigo: SIAL517933-25G
UOM: 1 * 25 g
Fornecedor: Merck
Image Unavailable-BOSSBS-0638R-HRP

Anti-TGFRB1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Descrição: Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
Código de Artigo: BOSSBS-0638R-HRP
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-0638R-A350

Anti-TGFRB1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Descrição: Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
Código de Artigo: BOSSBS-0638R-A350
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-SIAL345164-25G

Tin(II) acetate, Sigma-Aldrich®

Descrição: Tin(II) acetate, Sigma-Aldrich®
Código de Artigo: SIAL345164-25G
UOM: 1 * 25 g
Fornecedor: Merck
Image Unavailable-PRSI76-817

Anti-Cd69 Hamster Monoclonal Antibody [clone: H1.2F3]

Descrição: The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27 to 33 kDa type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Código de Artigo: PRSI76-817
UOM: 1 * 0,1 mg
Fornecedor: ProSci Inc.

Novo produto


Imagem do Produto-1.08525.0100

Ródio solução padrão, 10 mg/L Rh em 0,5 M ácido nítrico (de Rh(NO₃)₃) Certipur® padrão para ICP-MS, Supelco®

Descrição: Rhodium Standard, 10 mg/L, Certipur®, Supelco®, Ródio, Matriz: 0,5 M HNO₃, Aplicação: Padrões para ICP-MS
Código de Artigo: 1.08525.0100
UOM: 1 * 100 mL
Fornecedor: Merck

MSDS Certificados


Image Unavailable-SIAL339199-50G

Iron(II) acetate, Sigma-Aldrich®

Descrição: Iron(II) acetate, Sigma-Aldrich®
Código de Artigo: SIAL339199-50G
UOM: 1 * 50 g
Fornecedor: Merck
Image Unavailable-PRSI76-826

Anti-Cd69 Hamster Monoclonal Antibody [clone: H1.2F3] (APC (Allophycocyanin))

Descrição: The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27 to 33 kDa type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Código de Artigo: PRSI76-826
UOM: 1 * 0,1 mg
Fornecedor: ProSci Inc.

Novo produto


Image Unavailable-46523.NA

Rhodium(III) chloride solução 10 - 30% w/w (cont, Rh) 99.5% (w/w)

Descrição: Rhodium(III) chloride solução 10 - 30% w/w (cont, Rh) 99.5% (w/w)
Código de Artigo: 46523.NA
UOM: 1 * 2 g
Fornecedor: Thermo Fisher Scientific

MSDS


Image Unavailable-PRSI76-819

Anti-Cd69 Hamster Monoclonal Antibody [clone: H1.2F3]

Descrição: The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27 to 33 kDa type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Código de Artigo: PRSI76-819
UOM: 1 * 0,5 mg
Fornecedor: ProSci Inc.

Novo produto


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