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Image Unavailable-BOSSBS-8214R-CY5

Anti-FAM21C Rabbit Polyclonal Antibody (Cy5®)

Descrição: Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2/3 complex for induction of actin polymerization. FAM21, Putative WASH complex subunit FAM21, is a component of the WASH complex. Having undergone evolutionary duplication, four highly homologous family members exist including FAM21A, FAM21B, FAM21C and FAM21D. FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting. Also, by directly interacting with CapZ, FAM21 inhibits its anti-capping activity, thereby regulating actin dynamics.
Código de Artigo: BOSSBS-8214R-CY5
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-11364R-A750

Anti-SNAPIN/SNAP25BP Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Descrição: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialised organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
Código de Artigo: BOSSBS-11364R-A750
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-9723R-HRP

Anti-FAM29A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Descrição: The human augmin complex (HAUS) is an evolutionarily conserved 8-subunit protein complex that was initially discovered in Drosophila. The HAUS complex is essential for microtubule generation, centrosome integrity, mitotic spindle assembly and completion of cytokinesis. HAUS6 (HAUS augmin-like complex, subunit 6), also known as FAM29A or Dgt6, is a 955 amino acid component of the augmin complex. Required for mitotic progression, HAUS6 localizes to cytoplasm, cytoskeleton, mitotic spindle microtubules and interphase centrosomes, and undergoes post-translational phosphorylation following mitosis on multiple serine and threonine residues. HAUS6 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 9.
Código de Artigo: BOSSBS-9723R-HRP
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-9723R-CY3

Anti-FAM29A Rabbit Polyclonal Antibody (Cy3®)

Descrição: The human augmin complex (HAUS) is an evolutionarily conserved 8-subunit protein complex that was initially discovered in Drosophila. The HAUS complex is essential for microtubule generation, centrosome integrity, mitotic spindle assembly and completion of cytokinesis. HAUS6 (HAUS augmin-like complex, subunit 6), also known as FAM29A or Dgt6, is a 955 amino acid component of the augmin complex. Required for mitotic progression, HAUS6 localizes to cytoplasm, cytoskeleton, mitotic spindle microtubules and interphase centrosomes, and undergoes post-translational phosphorylation following mitosis on multiple serine and threonine residues. HAUS6 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 9.
Código de Artigo: BOSSBS-9723R-CY3
UOM: 1 * 100 µl
Fornecedor: Bioss
Imagem do Produto-BOSSBS-9723R

Anti-FAM29A Rabbit Polyclonal Antibody

Descrição: The human augmin complex (HAUS) is an evolutionarily conserved 8-subunit protein complex that was initially discovered in Drosophila. The HAUS complex is essential for microtubule generation, centrosome integrity, mitotic spindle assembly and completion of cytokinesis. HAUS6 (HAUS augmin-like complex, subunit 6), also known as FAM29A or Dgt6, is a 955 amino acid component of the augmin complex. Required for mitotic progression, HAUS6 localizes to cytoplasm, cytoskeleton, mitotic spindle microtubules and interphase centrosomes, and undergoes post-translational phosphorylation following mitosis on multiple serine and threonine residues. HAUS6 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 9.
Código de Artigo: BOSSBS-9723R
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-0024M-CY5

Anti-PSEN1 Mouse Polyclonal Antibody (Cy5®)

Descrição: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis (By similarity).
Código de Artigo: BOSSBS-0024M-CY5
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-0024M-CY7

Anti-PSEN1 Mouse Polyclonal Antibody (Cy7®)

Descrição: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis (By similarity).
Código de Artigo: BOSSBS-0024M-CY7
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-0633R-CY7

Anti-CDK4 Rabbit Polyclonal Antibody (Cy7®)

Descrição: Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
Código de Artigo: BOSSBS-0633R-CY7
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-323209-25G

4-(2-Pyridylazo)resorcinol 96%, Sigma-Aldrich®

Descrição: 4-(2-Pyridylazo)resorcinol (PAR) is a monosodium salt(1), dibasic acid that forms the protonated complexes with most metal ions.
Código de Artigo: 323209-25G
UOM: 1 * 25 g
Fornecedor: SIGMA ALDRICH MICROSCOPY
Imagem do Produto-ABCAAB109863-100

Anti-Complex IV Immunocapture Mouse Monoclonal Antibody [clone: 31E91B82G9]

Descrição: Mouse monoclonal [31E91B82G9] to Complex IV Immunocapture.
Código de Artigo: ABCAAB109863-100
UOM: 1 * 100 µG
Fornecedor: Abcam
Imagem do Produto-ABCAAB109865-100

Anti-Complex II Immunocapture Mouse Monoclonal Antibody [clone: 4H12BG12AG2]

Descrição: Mouse monoclonal [4H12BG12AG2] to Complex II Immunocapture.
Código de Artigo: ABCAAB109865-100
UOM: 1 * 100 µG
Fornecedor: Abcam
Imagem do Produto-USBIT2035-11-APC

Anti-T-complex Protein 1 Subunit gamma Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Descrição: Anti-T-complex Protein 1 Subunit gamma Rabbit Polyclonal Antibody (APC (Allophycocyanin))
Código de Artigo: USBIT2035-11-APC
UOM: 1 * 200 µl
Fornecedor: US Biological
Image Unavailable-USBI141887-50

Anti-Plasmin/Antiplasmin Complex Rabbit Polyclonal Antibody

Descrição: Anti-Plasmin/Antiplasmin Complex Rabbit Polyclonal Antibody
Código de Artigo: USBI141887-50
UOM: 1 * 50 µG
Fornecedor: US Biological
Image Unavailable-BOSSBS-6476R-A555

Anti-BAZ1A Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Descrição: Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.
Código de Artigo: BOSSBS-6476R-A555
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-6476R-A647

Anti-BAZ1A Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Descrição: Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.
Código de Artigo: BOSSBS-6476R-A647
UOM: 1 * 100 µl
Fornecedor: Bioss
Image Unavailable-BOSSBS-6476R-CY7

Anti-BAZ1A Rabbit Polyclonal Antibody (Cy7®)

Descrição: Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.
Código de Artigo: BOSSBS-6476R-CY7
UOM: 1 * 100 µl
Fornecedor: Bioss
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