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Image Unavailable-PRSI90-257

Human recombinant IZTRAIL (soluble) (from E. coli)

Código de Artigo: (PRSI90-257)
Fornecedor: ProSci Inc.
Descrição: izTRAIL is a newly available, highly active recombinant form of soluble human TRAIL. Due to a trimerizing N-terminal isoleucine zipper (iz) motif the intrinsic trimerization of TRAIL, required for apoptosis-inducing activity of TRAIL, is enhanced when compared to non-tagged soluble human TRAIL (shTRAIL). Therefore, izTRAIL is a potent inducer of apoptosis in many human cancer cells, but not normal human hepatocytes. In addition, the half-life of izTRAIL is about eight-fold higher than the half-life of shTRAIL. These properties render izTRAIL highly suitable for both in vitro and in vivo use, particularly for studies in which investigators plan to transfer their in vitro results into an in vivo system with human cancer cells in xenotransplant settings examining susceptibility to TRAIL-induced apoptosis.
UOM: 1 * 10 µG
Image Unavailable-VERN20-F

KryoSure® Cryopreservation Bag

Código de Artigo: (VERN20-F)
Fornecedor: Saint Gobain Life Sciences
Descrição: KryoSure® Cryopreservation bags safely freeze and protect biologics at temperatures down to, and even beyond, liquid nitrogen temperatures (–196 °C). All KryoSure® bags are made from the highest quality USP Class VI Fluorinated Ethylene Propylene (FEP) material.
UOM: 1 * 1 unid.

Novo produto


Image Unavailable-112-1249

Cut resistant chain gloves, Chainex 2000

Fornecedor: Honeywell Safety
Descrição: The Chainex 2000 is a full stainless steel glove with short cuff and attached textile strap. Chainex 2000 is a fully reversible product range, and is equipped with heavy duty adjustable straps and press stud fastening. Offers excellent cut and puncture protection. The high quality of the chain mesh reduces the numbers of repairs, and extends the life time of the glove.

Imagem do Produto-SARTSMB95-1003

Real-Time PCR kit for detection of mycoplasma, Microsart® ATMP Mycoplasma

Código de Artigo: (SARTSMB95-1003)
Fornecedor: Sartorius
Descrição: The Microsart® ATMP Mycoplasma detection kit is especially designed for an easy and fast detection of mycoplasma in cell-based therapeutics like autologous chondrocyte transplants (ATMPs –advanced therapy medical products). Due to the short shelf life of these therapeutics, a fast result is needed. The PCR-technology makes it possible to reduce the time-to-result to only 3 hours.
UOM: 1 * 1 unid.
Imagem do Produto-UPCHA-710

PEEK frits, Upchurch Scientific®

Fornecedor: UPCHURCH SCIENTIFIC
Descrição: Exceptionally uniform porosity which ensures longer filtration life and consistent frit-to-frit swept volumes. These frits are biocompatible and inert to most solvents, making them ideal for bioanalytical applications. The disc rings, made of PCTFE, are slightly thicker than the frit disc, providing enhanced sealing and excellent chemical resistance.

Imagem do Produto-786-257

FOCUS™ Yeast proteome kits

Código de Artigo: (786-257)
Fornecedor: G-Biosciences
Descrição: Specifically designed for yeast research and supplied with yeast specific reagents. Extracts and solubilises nearly all of the proteins from yeast, including membrane and soluble proteins. Extraction is based on gentle lysis of yeast cells with a yeast lytic enzyme preparation, LongLife™ Zymolyase®, which has improved stability and shelf life. Enzymatic action is followed by extraction of total proteome with the supplied strong chaotropic extraction buffer that solubilises even the most difficult proteins.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-3572R-HRP

Anti-SHC1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Código de Artigo: (BOSSBS-3572R-HRP)
Fornecedor: Bioss
Descrição: Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3410R-A488

Anti-SHC1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Código de Artigo: (BOSSBS-3410R-A488)
Fornecedor: Bioss
Descrição: Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3410R-A555

Anti-SHC1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Código de Artigo: (BOSSBS-3410R-A555)
Fornecedor: Bioss
Descrição: Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3410R-CY5

Anti-SHC1 Rabbit Polyclonal Antibody (Cy5®)

Código de Artigo: (BOSSBS-3410R-CY5)
Fornecedor: Bioss
Descrição: Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
UOM: 1 * 100 µl
Imagem do Produto-PRSI30-618

Anti-SHC1 Rabbit Polyclonal Antibody

Código de Artigo: (PRSI30-618)
Fornecedor: ProSci Inc.
Descrição: SHC1 is a signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span.
UOM: 1 * 50 µG
Imagem do Produto-PRSI79-235

Anti-SHC1 Rabbit Polyclonal Antibody

Código de Artigo: (PRSI79-235)
Fornecedor: ProSci Inc.
Descrição: Signaling adapter that couples activated growth factor receptors to signaling pathway. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span
UOM: 1 * 100 µG
Imagem do Produto-710-1700

Handheld colony counter, SP Bel-Art

Código de Artigo: (710-1700)
Fornecedor: Bel-Art Products, a Part of SP
Descrição: The display with backlight for easy viewing in low light conditions. The audible alert can be turned off if desired, and the counting function can be locked to prevent error during breaks between counting. The long life felt-tip markers (included) work on plastic or glass and are oil and water resistant. Ink marks are removable with ethyl alcohol.
UOM: 1 * 1 unid.

Certificados


Image Unavailable-BOSSBS-3412R-A750

Anti-SHC Tyr427 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Código de Artigo: (BOSSBS-3412R-A750)
Fornecedor: Bioss
Descrição: Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span. Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis. The expression of isoform p66Shc has been correlated with life span (By similarity). Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
UOM: 1 * 100 µl
Imagem do Produto-GESSPHFE6012503150

PharmaFluor® FEP Tubings

Código de Artigo: (GESSPHFE6012503150)
Fornecedor: Saint Gobain Life Sciences
Descrição: PharmaFluor® FEP fluoropolymer tubing meets the highest demands of biopharmaceutical, medical, and laboratory applications. This tubing is formulated to resist the absorption/adsorption of aqueous fluids, which minimises the risk of fluid alteration in single- or repeat- use applications. PharmaFluor FEP has outstanding chemical and physical characteristics and can be used in a broad range of temperatures, from −73 to +204 °C (−100 to +400 °F).
UOM: 1 * 50 pé
Imagem do Produto-HACH143203

Visual colour kit, detergents

Código de Artigo: (HACH143203)
Fornecedor: Hach
Descrição: It is a simple, economical colour disc kit to determine the presence of detergents in surface or ground waters which indicates industrial or domestic pollution. In natural waters anionic LAS and ABS detergents cause excessive foaming, promote growth of disease producing organisms and tend to kill aquatic life. This kit achieves fast results with an portable test kit.
UOM: 1 * 1 KIT
Preço sob consulta
O stock para este item é limitado. Por favor, certifique-se de que efetuou o seu login para visualizar o stock disponível. Se a call ainda é exibida e precisar de ajuda, por favor, ligue para 213 600 770
O stock para este item é limitado. Por favor, certifique-se de que efetuou o seu login para visualizar o stock disponível. Se a call está visível e precisar de ajuda, por favor, ligue para 213 600 770
Este produto é sujeito a regulamentação especifica.
Em caso de encomenda, será contactado a solicitar documentação complementar necessária e/ou obrigatória (licença, autorização ou declaração de uso final) para a continuidade do pedido. Agradecemos a vossa compreensão
Este produto é sujeito a regulamentação especifica.
Em caso de encomenda, será contactado a solicitar documentação complementar necessária e/ou obrigatória (licença, autorização ou declaração de uso final) para a continuidade do pedido. Agradecemos a vossa compreensão.
Este produto está bloqueado. Para obter mais informações, contacte a VWR através do número 213 600 770.
O produto pretendido já não se encontra disponível. O produto indicado é um substituto.
Este produto encontra-se em rutura de stock. Poderá encontrar alternativas pesquisando pelo código de artigo indicado acima. Se precisar de ajuda, por favor contacte a VWR através do 213 600 770.
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