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Image Unavailable-BOSSBS-1020R-PE

Anti-MAPK3 Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Código de Artigo: (BOSSBS-1020R-PE)
Fornecedor: Bioss
Descrição: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4(HSF4) (By similarity). Highest levels within the nervous system, expressed in different tissues, mostly in intestine, placenta and lung. Increased expression during development. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. Contains 1 protein kinase domain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1020R-CY5.5

Anti-MAPK3 Rabbit Polyclonal Antibody (Cy5.5®)

Código de Artigo: (BOSSBS-1020R-CY5.5)
Fornecedor: Bioss
Descrição: Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1. Phosphorylates heat shock factor protein 4(HSF4) (By similarity). Highest levels within the nervous system, expressed in different tissues, mostly in intestine, placenta and lung. Increased expression during development. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. Contains 1 protein kinase domain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9312R-A750

Anti-DIP2A/B/C Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Código de Artigo: (BOSSBS-9312R-A750)
Fornecedor: Bioss
Descrição: DIP2A, also known as DIP2, is a 1571 amino acid nuclear protein. It is one of three human homologs (DIP2A, DIP2B and DIP2C) of the Drosophila dip2 (disconnected-interacting protein 2) protein. In Drosophila, dip2 interacts with disco, a protein required for neuronal connections in the visual systems of larvae and adults. The closest vertebrate homologs to disco are the basonuclin genes. In mice, DIP2 homologs show restricted expression to the brain. This suggests that, similar to the function of Drosophila dip2, vertebrate DIP2 homologs may play a role in the development of the nervous system. Expressed ubiquitously with highest expression in the brain, DIP2A is thought to function in signaling throughout the central nervous system by providing positional clues for axon patterning and pathfinding. Four isoforms of DIP2A exist due to alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11807R-A750

Anti-Adracalin Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Código de Artigo: (BOSSBS-11807R-A750)
Fornecedor: Bioss
Descrição: Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterised by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11807R-A555

Anti-AAAS Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Código de Artigo: (BOSSBS-11807R-A555)
Fornecedor: Bioss
Descrição: Aladin (Adracalin) belongs to a family of WD repeat-containing proteins. These proteins have a wide variety of functions, including signal transduction regulation, RNA processing and transcription. Aladin plays a role in peripheral and central nervous system development. It is widely expressed, with the highest expression seen in pituitary gland, corpus callosum, cerebellum, adrenal gland and gastrointestinal structures. Defects in Aladin cause the autosomal recessive disorder achalasia-addisonianism-alacrima (triple A) syndrome. Triple A syndrome is characterized by achalasia, alacrima and adrenocortico-tropin-resistant adrenal insufficiency. Robust expression in neural systems associated with cognitive, motor and sensory functions is consistent with the myriad of symptoms experienced by patients with triple A syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12136R-A647

Anti-STRN4 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Código de Artigo: (BOSSBS-12136R-A647)
Fornecedor: Bioss
Descrição: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD-repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somatodendritic compartment, including spines, subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12135R-A488

Anti-STRN3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Código de Artigo: (BOSSBS-12135R-A488)
Fornecedor: Bioss
Descrição: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12135R-A647

Anti-STRN3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Código de Artigo: (BOSSBS-12135R-A647)
Fornecedor: Bioss
Descrição: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12136R-A555

Anti-STRN4 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Código de Artigo: (BOSSBS-12136R-A555)
Fornecedor: Bioss
Descrição: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD-repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somatodendritic compartment, including spines, subsets of neurons, and is considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8411R-A350

Anti-GLIPR2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Código de Artigo: (BOSSBS-8411R-A350)
Fornecedor: Bioss
Descrição: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8411R-A555

Anti-GLIPR2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Código de Artigo: (BOSSBS-8411R-A555)
Fornecedor: Bioss
Descrição: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8411R-A488

Anti-GLIPR2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Código de Artigo: (BOSSBS-8411R-A488)
Fornecedor: Bioss
Descrição: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12333R-CY3

Anti-ERMAP Rabbit Polyclonal Antibody (Cy3®)

Código de Artigo: (BOSSBS-12333R-CY3)
Fornecedor: Bioss
Descrição: ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, infant death.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12333R-CY7

Anti-ERMAP Rabbit Polyclonal Antibody (Cy7®)

Código de Artigo: (BOSSBS-12333R-CY7)
Fornecedor: Bioss
Descrição: ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, infant death.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2661R

Anti-LY86 Rabbit Polyclonal Antibody

Código de Artigo: (BOSSBS-2661R)
Fornecedor: Bioss
Descrição: MD1 is a 28 kDa molecule that is associated at the cell surface with RP105 (CD180). RP105 is a leucine-rich repeat (LRR) molecule that is expressed on B lymphocytes. It was first identified by a mAb that protects spleen B cells from irradiation-induced apoptosis. LRR proteins, such as Toll receptors, have a role in innate immunity. MD1 is primarily expressed by B cells, dendritic cells and monocytes, and promotes the recognition of, and subsequent signaling by LPS in the innate immune system. MD1 does not have any homology to other molecules. MD1 when expressed alone behaves as a secretory protein. Expression of MD1 in a cell increases the expression of RP105.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10109R-A750

Anti-Tau protein Ser531 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Código de Artigo: (BOSSBS-10109R-A750)
Fornecedor: Bioss
Descrição: Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localisation (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilisation. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
UOM: 1 * 100 µl
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O stock para este item é limitado. Por favor, certifique-se de que efetuou o seu login para visualizar o stock disponível. Se a call ainda é exibida e precisar de ajuda, por favor, ligue para 213 600 770
O stock para este item é limitado. Por favor, certifique-se de que efetuou o seu login para visualizar o stock disponível. Se a call está visível e precisar de ajuda, por favor, ligue para 213 600 770
Este produto é sujeito a regulamentação especifica.
Em caso de encomenda, será contactado a solicitar documentação complementar necessária e/ou obrigatória (licença, autorização ou declaração de uso final) para a continuidade do pedido. Agradecemos a vossa compreensão
Este produto é sujeito a regulamentação especifica.
Em caso de encomenda, será contactado a solicitar documentação complementar necessária e/ou obrigatória (licença, autorização ou declaração de uso final) para a continuidade do pedido. Agradecemos a vossa compreensão.
Este produto está bloqueado. Para obter mais informações, contacte a VWR através do número 213 600 770.
O produto pretendido já não se encontra disponível. O produto indicado é um substituto.
Este produto encontra-se em rutura de stock. Poderá encontrar alternativas pesquisando pelo código de artigo indicado acima. Se precisar de ajuda, por favor contacte a VWR através do 213 600 770.
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