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Image Unavailable-BOSSBS-13035R-A555

Anti-DUSP10 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Código de Artigo: (BOSSBS-13035R-A555)
Fornecedor: Bioss
Descrição: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. MKP-5 preferentially binds to p38, but also to SAPK/JNK. It is ubiquitously expressed and localizes to both the cytoplasm and the nucleus. MKP-5 has been implicated in cell proliferation and apoptosis, tumor invasion and immune responses.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5179R-A680

Anti-PTPRA Tyr798 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Código de Artigo: (BOSSBS-5179R-A680)
Fornecedor: Bioss
Descrição: Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5175R-A750

Anti-PTPRA Ser180 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Código de Artigo: (BOSSBS-5175R-A750)
Fornecedor: Bioss
Descrição: Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5175R-A680

Anti-PTPRA Ser180 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Código de Artigo: (BOSSBS-5175R-A680)
Fornecedor: Bioss
Descrição: Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5179R-A750

Anti-PTPRA Tyr798 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Código de Artigo: (BOSSBS-5179R-A750)
Fornecedor: Bioss
Descrição: Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13280R-A555

Anti-RASA1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Código de Artigo: (BOSSBS-13280R-A555)
Fornecedor: Bioss
Descrição: The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13280R-CY3

Anti-RASA1 Rabbit Polyclonal Antibody (Cy3®)

Código de Artigo: (BOSSBS-13280R-CY3)
Fornecedor: Bioss
Descrição: The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13281R-A750

Anti-RASA1 Tyr460 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Código de Artigo: (BOSSBS-13281R-A750)
Fornecedor: Bioss
Descrição: The mammalian c-H-, c-K- and N-Ras proto-oncogenes encode ubiquitously expressed proteins (1,2). p21Ras can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (3). Oncogenic p21Ras proteins are trapped in the excited signal-emitting state because the mechanism normally employed to delimit their excitation period, hydrolysis of their bound GTP to GDP, is impaired as a result of specific mutations (3). Interaction of p21Ras with GTPase activating protein (GAP) can increase hydrolysis of p21Ras-bound GTP by as much as 1000-fold (4,5). The product of the neurofibromatosis type 1 gene (NF1) has also been shown to exhibit p21Ras GAP activity (6,7), and proteins that stimulate the GTPase activity of three other low molecular weight GTPases, including Rho, Rab 3A and Rap 1, have also been described (8,9).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2883R-A488

Anti-S1PR4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Código de Artigo: (BOSSBS-2883R-A488)
Fornecedor: Bioss
Descrição: This protein belongs to a G protein coupled heptahelical receptor subfamily named Endothelial Cell Differentiation Genes (EDG)that act as receptors for biologically active lysophospholipids. This group consists of two receptor subgroups specific for S1P and LPA respectively. EDG6 is the receptor for lysophospholipid sphingosine 1 phosphate (S1P). S1P elicits diverse physiological effect on most types of cells and tissues. EDG6 may be involved in cell migration processes that are specific for lymphocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2883R-CY3

Anti-S1PR4 Rabbit Polyclonal Antibody (Cy3®)

Código de Artigo: (BOSSBS-2883R-CY3)
Fornecedor: Bioss
Descrição: This protein belongs to a G protein coupled heptahelical receptor subfamily named Endothelial Cell Differentiation Genes (EDG)that act as receptors for biologically active lysophospholipids. This group consists of two receptor subgroups specific for S1P and LPA respectively. EDG6 is the receptor for lysophospholipid sphingosine 1 phosphate (S1P). S1P elicits diverse physiological effect on most types of cells and tissues. EDG6 may be involved in cell migration processes that are specific for lymphocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2883R-CY5.5

Anti-S1PR4 Rabbit Polyclonal Antibody (Cy5.5®)

Código de Artigo: (BOSSBS-2883R-CY5.5)
Fornecedor: Bioss
Descrição: This protein belongs to a G protein coupled heptahelical receptor subfamily named Endothelial Cell Differentiation Genes (EDG)that act as receptors for biologically active lysophospholipids. This group consists of two receptor subgroups specific for S1P and LPA respectively. EDG6 is the receptor for lysophospholipid sphingosine 1 phosphate (S1P). S1P elicits diverse physiological effect on most types of cells and tissues. EDG6 may be involved in cell migration processes that are specific for lymphocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2883R-FITC

Anti-S1PR4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Código de Artigo: (BOSSBS-2883R-FITC)
Fornecedor: Bioss
Descrição: This protein belongs to a G protein coupled heptahelical receptor subfamily named Endothelial Cell Differentiation Genes (EDG)that act as receptors for biologically active lysophospholipids. This group consists of two receptor subgroups specific for S1P and LPA respectively. EDG6 is the receptor for lysophospholipid sphingosine 1 phosphate (S1P). S1P elicits diverse physiological effect on most types of cells and tissues. EDG6 may be involved in cell migration processes that are specific for lymphocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2883R-CY7

Anti-S1PR4 Rabbit Polyclonal Antibody (Cy7®)

Código de Artigo: (BOSSBS-2883R-CY7)
Fornecedor: Bioss
Descrição: This protein belongs to a G protein coupled heptahelical receptor subfamily named Endothelial Cell Differentiation Genes (EDG)that act as receptors for biologically active lysophospholipids. This group consists of two receptor subgroups specific for S1P and LPA respectively. EDG6 is the receptor for lysophospholipid sphingosine 1 phosphate (S1P). S1P elicits diverse physiological effect on most types of cells and tissues. EDG6 may be involved in cell migration processes that are specific for lymphocytes.
UOM: 1 * 100 µl
Imagem do Produto-PRSI36-228

Anti-IDO1 Rabbit Polyclonal Antibody

Código de Artigo: (PRSI36-228)
Fornecedor: ProSci Inc.
Descrição: IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-5933R-CY3

Anti-KCNK1 Rabbit Polyclonal Antibody (Cy3®)

Código de Artigo: (BOSSBS-5933R-CY3)
Fornecedor: Bioss
Descrição: KCNK9 or TASK-3 (TWIK-related Acid sensitive K+ channel) is a member of the potassium channel family of proteins that contain two-pore domain and four transmembrane domains. These channels are characterized as leak K+ channels that are sensitive to changes in the extracellular pH. The physiological functions of TASK channels are largely unknown; it has been proposed that they may be involved in the regulation of breathing, aldosterone secretion and anesthetic-mediated neuronal activity. They were found to act in neurons' membrane potential and in resting K+ currents.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1238R-A555

Anti-HMOX2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Código de Artigo: (BOSSBS-1238R-A555)
Fornecedor: Bioss
Descrição: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
UOM: 1 * 100 µl
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O stock para este item é limitado. Por favor, certifique-se de que efetuou o seu login para visualizar o stock disponível. Se a call ainda é exibida e precisar de ajuda, por favor, ligue para 213 600 770
O stock para este item é limitado. Por favor, certifique-se de que efetuou o seu login para visualizar o stock disponível. Se a call está visível e precisar de ajuda, por favor, ligue para 213 600 770
Este produto é sujeito a regulamentação especifica.
Em caso de encomenda, será contactado a solicitar documentação complementar necessária e/ou obrigatória (licença, autorização ou declaração de uso final) para a continuidade do pedido. Agradecemos a vossa compreensão
Este produto é sujeito a regulamentação especifica.
Em caso de encomenda, será contactado a solicitar documentação complementar necessária e/ou obrigatória (licença, autorização ou declaração de uso final) para a continuidade do pedido. Agradecemos a vossa compreensão.
Este produto está bloqueado. Para obter mais informações, contacte a VWR através do número 213 600 770.
O produto pretendido já não se encontra disponível. O produto indicado é um substituto.
Este produto encontra-se em rutura de stock. Poderá encontrar alternativas pesquisando pelo código de artigo indicado acima. Se precisar de ajuda, por favor contacte a VWR através do 213 600 770.
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