Procurou por: Noc-5

Código de Artigo: (ANTIA99018-100)

Fornecedor: ANTIBODIES.COM

Descrição: Rabbit polyclonal antibody to NOC3L for WB and ELISA with samples derived from human and mouse.

UOM: 1 * 100 µG

Novo produto Promoção

Código de Artigo: (ORIGTA308762)

Fornecedor: OriGene

Descrição: Anti-SOCS5 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Promoção

Código de Artigo: (PRSI46-411)

Fornecedor: ProSci Inc.

Descrição: Anti-SOCS5 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promoção

Código de Artigo: (PRSI19-075)

Fornecedor: ProSci Inc.

Descrição: Anti-NCOA5 Rabbit Polyclonal Antibody

UOM: 1 * 50 µl

Promoção

Código de Artigo: (ANTIA83737-100)

Fornecedor: ANTIBODIES.COM

Descrição: Goat polyclonal antibody to SOCS5 for ELISA and WB with samples derived from human.

UOM: 1 * 100 µG

Novo produto Promoção

Código de Artigo: (ABNOH00009655-B01P)

Fornecedor: Abnova

Descrição: Anti-SOCS5 Mouse Polyclonal Antibody

UOM: 1 * 50 µG

Promoção

Código de Artigo: (BOSSBS-13664R-FITC)

Fornecedor: Bioss

Descrição: The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-13664R-A680)

Fornecedor: Bioss

Descrição: The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS. Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box. The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction. Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways. During Th1 differentiation a reduction in the association of Jak1 with the IL4 Receptor correlated with the appearance of SOCS5. SOCS5 protein was preferentially expressed in committed Th1 cells and interacted with the cytoplasmic region of the IL4 Receptor alpha chain irrespective of receptor tyrosine phosphorylation. This unconventional interaction of SOCS5 protein with IL4 Receptor resulted in the inhibition of IL4-mediated signal transducer and activator of transcription-6 activation. T cells from transgenic mice constitutively expressing SOCS5 exhibited a significant reduction of IL4-mediated Th2 development. Therefore, the induced SOCS5 protein in Th1 differentiation environment may play an important role by regulating Th1 and Th2 balance.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-7618R-A750)

Fornecedor: Bioss

Descrição: NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-7618R-FITC)

Fornecedor: Bioss

Descrição: NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (USBI039040-AP)

Fornecedor: US Biological

Descrição: Anti-NOC3L Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

UOM: 1 * 200 µl

Promoção

Código de Artigo: (USBI039040-FITC)

Fornecedor: US Biological

Descrição: Anti-NOC3L Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

UOM: 1 * 200 µl

Promoção

Código de Artigo: (ORIGTA315722)

Fornecedor: OriGene

Descrição: Anti-NOC3L Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Promoção

Fornecedor: Biorbyt

Descrição: Anti-NOC3L Rabbit Polyclonal Antibody

Código de Artigo: (ANTIA97388-100)

Fornecedor: ANTIBODIES.COM

Descrição: Rabbit polyclonal antibody to NOC2L for WB and ELISA with samples derived from Human, Mouse and Rat.

UOM: 1 * 100 µG

Novo produto Promoção

Código de Artigo: (ABNOH00009655-D01P)

Fornecedor: Abnova

Descrição: Anti-SOCS5 Rabbit Polyclonal Antibody

UOM: 1 * 100 µG

Promoção