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Procurou por: gegenie


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Descrição: Epstein-Barr virus induced gene-3 (EBI3) is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). EBI3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form interleukin 27 (IL-27), and with p35 to form interleukin 35 (IL-35). Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.
Código de Artigo: SHBT100-162AF-5UG
UOM: 1 * 5 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Monocyte chemotactic protein 3 (MCP-3), also called CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis.
Código de Artigo: SHBT300-07-100UG
UOM: 1 * 100 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Myostatin, also known as GDF-8, is a conserved member of the TGF-beta superfamily. Myostatin is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size.
Código de Artigo: SHBT100-22-10UG
UOM: 1 * 10 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Interleukin 8 (IL-8 or CXCL8) is a member of the CXC cytokine family and is produced by macrophages, epithelial, smooth muscle, and endothelial cells. IL-8 binds the  G protein-coupled serpentine receptors CXCR1 and CXCR2. IL-8 recruits innate immune cells, induces phagocytosis, and stimulates angiogenesis.
Código de Artigo: SHBT400-03-100UG
UOM: 1 * 100 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
Código de Artigo: SHBT100-175-100UG
UOM: 1 * 100 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.
Código de Artigo: SHBT200-37AF-1MG
UOM: 1 * 1 mg
Fornecedor: Shenandoah Biotechnology


Descrição: Growth regulated protein beta (GRO-β), also known as CXCL2, is a chemokine that is secreted by macrophages, neutrophils, and monocytes at sites of inflammation. GRO-β functions as a chemoattractant for leukocytes and hematopoietic stem cells. GRO-β activity is mediated through binding the G-protein-coupled chemokine receptor CXCR2.
Código de Artigo: SHBT100-123-100UG
UOM: 1 * 100 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
Código de Artigo: SHBT100-17AF-10UG
UOM: 1 * 10 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Connective tissue growth factor (CTGF) is a mitogen that is secreted by vascular endothelial cells in response to basic fibroblast growth factor (bFGF) or vascular endothelial growth factor (VEGF). CTGF promotes cell growth, migration, adhesion, and survival of endothelial cells.
Código de Artigo: SHBT100-55AF-5UG
UOM: 1 * 5 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes.  IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.
Código de Artigo: SHBT200-17AF-1MG
UOM: 1 * 1 mg
Fornecedor: Shenandoah Biotechnology


Descrição: Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family. TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. TGF-α functions as a mitogen to activate epithelial cell proliferation, growth, and differentiation.
Código de Artigo: SHBT100-204AF100UG
UOM: 1 * 100 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Fibroblast growth factor 8 (FGF-8) is a critical mitogenic factor that is required for normal development of the eye, ear, brain, and limb. FGF-8 functions broadly to promote cell proliferation, differentiation, and migration. Overexpression of FGF-8 increases tumor growth and angiogenesis. Human and mouse FGF-8 proteins show 100% homology.
Código de Artigo: SHBT800-03-5UG
UOM: 1 * 5 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Pleiotrophin (PTN) is a heparin-binding growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells. PTN is made by many tissues, but is predominantly secreted by nervous tissue during development. PTN induces neurite outgrowth and is involved in tumor growth and metastasis.
Código de Artigo: SHBT100-50-100UG
UOM: 1 * 100 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Interleukin 8 (IL-8 or CXCL8) is a member of the CXC cytokine family and is produced by macrophages, epithelial, smooth muscle, and endothelial cells. IL-8 binds the  G protein-coupled serpentine receptors CXCR1 and CXCR2. IL-8 recruits innate immune cells, induces phagocytosis, and stimulates angiogenesis.
Código de Artigo: SHBT400-03AF-1MG
UOM: 1 * 1 mg
Fornecedor: Shenandoah Biotechnology


Descrição: Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.
Código de Artigo: SHBT100-02AF-500UG
UOM: 1 * 500 µG
Fornecedor: Shenandoah Biotechnology


Descrição: Pleiotrophin (PTN) is a heparin-binding growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells. PTN is made by many tissues, but is predominantly secreted by nervous tissue during development. PTN induces neurite outgrowth and is involved in tumor growth and metastasis.
Código de Artigo: SHBT100-55-5UG
UOM: 1 * 5 µG
Fornecedor: Shenandoah Biotechnology


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