Procurou por: Tampões de ajuste de força iónica

Código de Artigo: (BOSSBS-3284R-A750)

Fornecedor: Bioss

Descrição: MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-3284R-A680)

Fornecedor: Bioss

Descrição: MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-11393R-A555)

Fornecedor: Bioss

Descrição: May play a role in prolonged long term-potentiation (LTP) maintenance.

UOM: 1 * 100 µl

Promoção

Fornecedor: SIGMA ALDRICH MICROSCOPY

Descrição: 10% Neutral buffered formalin (NBF) is the most commonly used fixative for light microscopy. 10% NBF is well suited for large throughput laboratories and requires a relatively short period of fixation, but can also be used for the long-term storage of tissue. Formalin fixation is thought to form between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship.

Código de Artigo: (BOSSBS-2685R-A680)

Fornecedor: Bioss

Descrição: Receptor for TNFSF4/OX4L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-2685R-FITC)

Fornecedor: Bioss

Descrição: Receptor for TNFSF4/OX4L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-13136R-CY5)

Fornecedor: Bioss

Descrição: Required for long-term survival of nociceptive and autonomic ganglion neurons.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-13136R)

Fornecedor: Bioss

Descrição: Required for long-term survival of nociceptive and autonomic ganglion neurons.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-11950R-HRP)

Fornecedor: Bioss

Descrição: Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses.

UOM: 1 * 100 µl

Promoção

Fornecedor: PROTIDE PHARMACEUTICALS

Descrição: Ready to use, balanced, cytoprotective, protein-free solution with bio-stabilisers for short-term storage, regenerative medicine, stem cell processing and transportation of biological material. Short-term storage can be achieved at 2 to 8 °C or at ambient temperature for 24 to 48 hours. Does not contain any growth factors, hormones, or antibiotics. 2-8CELLsius™ can also be utilised as a cell washing solution.

Código de Artigo: (BSENR-1707-100)

Fornecedor: Biosensis

Descrição: BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 100 µG

Promoção

Código de Artigo: (BSENM-1736-50)

Fornecedor: Biosensis

Descrição: BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 50 µG

Promoção

Código de Artigo: (BOSSBS-11393R-CY3)

Fornecedor: Bioss

Descrição: May play a role in prolonged long term-potentiation (LTP) maintenance.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-13136R-A647)

Fornecedor: Bioss

Descrição: Required for long-term survival of nociceptive and autonomic ganglion neurons.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-13136R-A350)

Fornecedor: Bioss

Descrição: Required for long-term survival of nociceptive and autonomic ganglion neurons.

UOM: 1 * 100 µl

Promoção

Código de Artigo: (BOSSBS-13136R-HRP)

Fornecedor: Bioss

Descrição: Required for long-term survival of nociceptive and autonomic ganglion neurons.

UOM: 1 * 100 µl

Promoção