Benzo[a]pireno ≥96% (por HPLC), Sigma-Aldrich®
Fornecedor: Merck
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Perigo
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Nível de qualidade M-Clarity™ = MQ200
B1760-1G
B1760-100MG
B1760-500MG
B1760-5G
SIALB1760-1GEA
678
EUR
SIALB1760-1G
SIALB1760-100MG
SIALB1760-500MG
SIALB1760-5G
Benzo[a]pireno ≥96% (por HPLC), Sigma-Aldrich®
Benzo[a]pireno
Benzo[a]pyrene (PAH), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer.
Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.
Fórmula:
C₂₀H₁₂ Ponto de ebulição: 495 °C (1013 hPa) Ponto de Fusão: 176…178 °C Densidade: 1,351 g/cm³ (20 °C) |
Número MDL :
MFCD00003602 Número CAS: 50-32-8 EINECS: 200-028-5 UN: 2811 ADR: 6.1,III Merck Index: 12,01134 |
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