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Cloreto de guanidínio 99, powder_crystalline_white, ultrapure

Fornecedor: MP Biomedicals
Atenção

Sinônimos: Guanadine hydrochloride, Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidine HCI, Guanidine chloride, Guanidinium chloride, Guanidine hydrochloride

04820512 04820539 04820540
ICNA04820512EA 78.1 EUR
ICNA04820512 ICNA04820539 ICNA04820540
Cloreto de guanidínio 99, powder_crystalline_white, ultrapure
Cloreto de guanidínio

Guanidine Hydrochloride is a protein denaturant and thus having an important role in molecular weight determinations.
Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine HCl is used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties. It is an inhibitor of RNase. Highly concentrated (6 - 8 M) Guanidine HCl solutions are used to denature native globular proteins. It apparently disrupts hydrogen bonds which hold the protein in its unique structure. However, there also is evidence suggesting that guanidine hydrocholoride may disrupt hydrophobic interactions by promoting the solubility of hydrophobic residues in aqueous solutions.


  • Ultra Pure Grade
  • Suitable for molecular biology applications
  • White Crystalline Powder
  • pKa: 13.6 (Lit.)
  • Store at Room Temperature (15-30 °C). Store Desiccated.


pH: 4 - 6 (6.0 M aq soln) (Lit.)

Fórmula: NH₂C(=NH)NH₂·HCl
Peso Molecular: 95.53 g/mol
Ponto de Fusão: 180…190 °C
Temperatura de Armazenamento: Ambiente
Número MDL : MFCD00013026
Número CAS: 50-01-1
Merck Index: 13,04578
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Especificações dos Resultados do Teste

Identity Test Passes
Purity ≥99%
FTIR Conforms to Standard
pH (6.0 M aq soln) 4-6
OD260 (6.0M aq soln) ≤0.03
Loss on Drying ≤1.0%
Solubility (6.0 M aq soln) Clear, Colorless Solution


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