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Anti-UACA Mouse Monoclonal Antibody (Biotin) [clone: AE-5]

Fornecedor: Biotium
BNCB0956-500 BNCB0956-100
BNCB0956-500EA 560 EUR
BNCB0956-500 BNCB0956-100
Anti-UACA Mouse Monoclonal Antibody (Biotin) [clone: AE-5]
Anticorpos
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Type: Primary
Antigen: UACA
Clonality: Monoclonal
Clone: AE-5
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse
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