Spermine-(N,N'-bis(3-aminopropyl)-1,4-butanediamine) 97, solid_colorless
Fornecedor: MP Biomedicals
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Perigo
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Sinônimos:
N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine), Spermine
Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.
Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether.
Atenção: Research Use Only (RUO). Desiccate, store under nitrogen.
Fórmula:
C₁₀H₂₆N₄ Peso Molecular: 202.35 g/mol Ponto de ebulição: 141…142 °C (0.5 mmHg) Ponto de Fusão: 28…30 °C (literatura) Temperatura de Armazenamento: Frigorífico |
Número MDL :
MFCD00008215 Número CAS: 71-44-3 |
Especificações dos Resultados do Teste
Identity Test | Passes |
Purity | ≥97% |
FTIR | Conforms to Standard |
pH (0.5% aq soln) | 11 - 14 |
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