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Anti-CDKN2A Mouse Monoclonal Antibody

Fornecedor: ProSci Inc.
32-172
PRSI32-172EA 549 EUR
PRSI32-172
Anti-CDKN2A Mouse Monoclonal Antibody
Anticorpos
p16 (cyclin-dependent kinase inhibitor 2A, INK4a) is a tumor suppressor protein. It is a specific inhibitor of Cdk 4 / Cdk 6, and a tumor suppressor involved in the pathogenesis of a variety of malignancies. Recent analyses of the p16 INK4a gene revealed homozygous deletions, nonsense, missense, or frameshift mutations in several human cancers. Although the frequency of p16 INK4a abnormalities is higher in tumor derived cell lines than in unselected primary tumors, significant subsets of clinical cases with aberrant p16 INK4a gene have been reported among melanomas, gliomas, esophageal,Mais informação do produto
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