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Anti-GMDS Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Fornecedor: Bioss
BS-13453R-A350
BOSSBS-13453R-A350EA 893 EUR
BOSSBS-13453R-A350
Anti-GMDS Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Anticorpos
GMD is a 372 amino acid protein that utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. GMD mutations are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. The gene encoding GMD maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda,Mais informação do produto
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