Print…

Anti-ABH1/ALKB Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Fornecedor: Bioss
BS-12565R-A750
BOSSBS-12565R-A750EA 890 EUR
BOSSBS-12565R-A750
Anti-ABH1/ALKB Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anticorpos
ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumourMais informação do produto
Encomendar

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mais info About VWR